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Central line associated bloodstream infections

After prolonged use, the central line catheter can get seeded, and can inturn cause a bloodstream infection.  When the central line catheter becomes infected, it should be pulled "immediately".  However,  sometimes, a central line catheter is necessary, and cannot be easily reinserted.  In such scenarios, and in the absence of a definite diagnostic test that can diagnose CLABSI, clinicians must use their best judgement.

Diagnosing CLABSI

InSpector-01 can help diagnose CLABSI.  The diagnosis of CLABSI involves 3 parts:  (a) blood drawn from both the central line, and from peripheral sites must both be infected (b) with the same pathogen & (c) the concentration at the central line site must be 3X greater than at the periphery.

The quantification of the pathogen concentration is problematic ~ the only way to do so right now is via the "differential time to positivity" in the blood culture, which is not very precise, and which takes over 24 hours.

InSpector-01 provides a semi-quantitative output of pathogen concentration.  Thus, InSpector-01 can help rapidly diagnose CLABSI